Pathology as a practice vitally relies on the accurate interpretation of microscopic images in order to correctly diagnose patients and guide therapeutic decision making. With the advent of whole slide imaging (WSI), pathologists have begun to transfer the act of viewing glass slides from the microscope to the computer monitor. Using modern WSI systems, pathologists can navigate a virtual slide in much the same way they navigate Google Maps. This has led to a number of new opportunities not possible using conventional microscopes, including digital collaboration/telepathology, integration with electronic workflows and health records, and diagnostic support based on computational tools like artificial intelligence. The regulatory apparatus that governs this technology in the United States is just starting to come together, with US Food and Drug Administration (FDA) clearance having been granted only a year ago and accreditation agencies still working to establish comprehensive policies that ensure proper validation and use.1 Nevertheless, its role in clinical diagnostics, education, and research has begun to materialize, and rapid adoption of WSI in pathology laboratories will likely follow. This white paper outlines the current state of WSI in pathology, emphasizing the practical considerations for adoption and the regulatory guidelines that govern its use. Additionally, we present several areas of ongoing research and development poised to introduce transformative prognostic and predictive capabilities to pathology. BASICS OF OPERATION Whole slide imaging encompasses the digitization of entire histology slides or preselected areas. It was first ….. follow this link to read this article. https://www.archivesofpathology.org/doi/pdf/10.5858/arpa.2018-0343-RA
